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EARLY LIFE STRESS DECREASES THE PROLIFERATION AND NUMBERS OF ADULT HYPOTHALAMIC NEURAL STEM CELLS.

November 5, 2019

Our new article describing for the first time the effects of early life stress on hypothalamic neural stem cells is now freely available on bioRxiv, have a look!

https://www.biorxiv.org/content/10.1101/831446v1

OUR RECENT ARTICLE IS PUBLISHED IN MOLECULAR PSYCHIATRY

June 2019

A decrease in adult hippocampal neurogenesis has been linked to age-related cognitive impairment. However, the mechanisms involved in this age-related reduction remain elusive.  Here, we show that circadian oscillations in glucocorticoid hormones prevent neural stem cell activation and preserve a quiescent neural stem pool in the aging hippocampus that contributes to a neuroplasticity reserve in the aging brain.

The full text is accessible open-access following the link:

https://www.nature.com/articles/s41380-019-0440-2

 
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